BioArchive® Storage System
90% of the world's major blood banks 75% of all cord blood banks in Europe BioArchive® system, the only bank in Turkey to offer the BioArchive® system Babylife Cord Blood Bankis. The storage conditions and technology are as important as the storage of cord blood. Storage conditions are the most important factor in how long blood can be stored. Below BioArchive® systemn advantages and differences from traditional storage tanks used by other banks.
> Specially designed for stem cell storage.
> Approved by the US Food and Drug Administration (FDA).
> It is used by 129 cord blood banks in 37 countries.
> It is used by major blood banks worldwide, 90% of cord blood banks in Europe and the New York Blood Center, the world's first cord blood bank, which performs the majority of transplants worldwide.
> Provided stem cell samples for over 75% of global cord blood transplants 17
> Storage and retrieval performed by a fully automated robotic arm.
> "Transient Warming Event" (TWE), which is the biggest factor that reduces the chances of a possible transfer in conventional tanks, is not experienced in this system. 18
> For long-term stem cell storage, liquid nitrogen (constant temperature at -196˚C) medium recommended in research reports is used.
> Built-in computerized record-tracking system with precise storage-retrieval recording.
> The liquid nitrogen reservoir can maintain a constant temperature of -196 ˚C for more than 50 days in the event of a power outage.
Cell Viability is Key to Successful Transplant Rate
Cord blood and umbilical cord storage provides lifelong protection for your children and family. No one wants to have the chance to use it one day. But if necessary, do you know that the low viability of stem cells would allow the cord blood and umbilical cord to lose their function? Babylife, accepted by most public blood banks in the world (including the New York Cord Blood Center, Tokyo Cord Blood Bank and major blood banks worldwide) BioArchive® is the sole representative of the liquid nitrogen storage system in Turkey. Reports on the use of liquid nitrogen (constant temperature at -196°C) as storage medium, long-term stem cell storage recommended by the Center for the Study of Cord Blood Stem Cells. Only liquid nitrogen can remain stable at -196°C and all physiological activities of cord blood stem cells are suspended at this temperature. Stored cells must remain at this temperature to maintain their viability for many years. Otherwise Temporary Warming (TWE) will result in reduced cell viability, which could jeopardize transplant success if blood is needed for transplantation in the future.
BioArchive ® System |
Traditional Tanks |
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| Authenticity | ✅ Specially designed for stem cell storage | Χ General purpose for the storage of biological samples |
| Special advanced technology to protect the baby's precious stem cells. | ||
| Storage Environment |
✅ Stable temperature to ensure optimal stem cell viability
✅ Permanent storage at constant temperature (-196˚C) for more than 1000 years ✅ The liquid nitrogen reservoir can preserve stem cells without any temperature rise for more than 50 days without electricity supply. |
Χ Lower cell viability as a result of continuous temperature fluctuations (TWE-Transient Warming Event)
Χ There is no scientific evidence that nitrogen vapor can be used for long-term storage Χ Samples in nitrogen vapor can only be stored for ~20 days |
| Size Plus | The BioArchive® system, which is much more costly than traditional tanks, is used only by Babylife in Turkey to preserve the viability of stem cells at the maximum level. | |
| Design and Management |
✅ Closed design with constant storage temperature
✅ Thanks to the robotic arm, other blood is not affected during blood storage and collection. ✅ "Transient warming" (TWE) is eradicated (completely destroyed), ensuring high stem cell viability. ✅ 24-hour active internal surveillance system with instant alarm ✅ Manual mode for accessing samples in an emergency ✅ Contains only sample records, no risk of personal data being accessed ✅ Independent periscope access to samples without interfering with others |
Χ Open system that allows for in-tank temperature imbalances and bacterial contamination during storage and collection of blood
Χ The "transient warming" (TWE) that takes place during the sampling-retrieval process in a conventional tank can lead to a decrease in the viability of all cells in the tank. Χ Non-inclusive and outdated system based on external observation Χ Manual operation with a high risk of human error, inviting mistakes
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| Size Plus | The fully automated closed system can avoid manual errors and TWEs that can affect the quality of cord blood and cord stem cells. | |
| Controlled Freezing Speed |
✅ The integrated controlled freezer system prevents "transient warming" (TWE).
✅ Optimum freezing rate for stem cell viability 2.8℃/min |
Χ The external freezing procedure causes samples to be exposed from -190℃ to room temperature. The extreme temperature difference causes severe damage to stem cells (2-4% loss)
Χ Prolonged and uncontrolled freezing process (~120 min) |
| Size Plus | A special integrated controlled-speed freezer allows processes to be completed in a short and controlled time. | |
| Stem Cell Quality |
✅ Undeniable superiority over other storage methods with over 97% CD34+ viability
✅ More than 94% cell viability after solubilization |
Χ 20% reduction in cell viability due to the combined effect of nitrogen vapor and "transient heating" |
| Size Plus | Using a closed system and liquid nitrogen as a storage medium preserves stem cells with high viability for many years for future use. | |
| Successful Transplant |
✅ Post-transplant survival rate is 10% higher than conventional tanks
✅ Provided 75% of successful transplants worldwide |
Χ Lower chances of success due to reduced vitality, especially "transient warming" |
| Size Plus | Patient survival rate of patient receiving stem cells for transplantation from BioArchive® system is 10% higher than those using conventional nitrogen vapor storage system | |
| Global Usage |
✅ 80% of Netcord member cord blood banks use
✅ Preferred by most public blood banks worldwide (New York Cord Blood Center, Tokyo Cord Blood Bank, etc.)
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Χ It is preferred by private cord blood banks in Turkey due to its low installation and operating costs. |
| Size Plus | Babylife is the only company in Turkey that uses this system, whose superiority is incomparable with the leading banks in the world. | |
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Cross-contamination |
✅ No record of cross contamination
✅Cordblood, whether in liquid nitrogen or nitrogen vapor, can be cross-contaminated unless it is completely airtight ✅Reports showed that sealed BioArchive® storage cassettes (each stem cell has its own sealed cassette) can eliminate cross-contamination with liquid nitrogen storage
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Χ Cross-contamination cases have occurred |
Transient Warming Events (TWEs) - Reduce Stem Cell Viability and Impact Transplant Quality
Transient Warming Event refers to a situation in which cord blood stem cells, frozen at -196°C, are temporarily exposed to air at normal temperature while they are taken out of the storage tank, other cord blood is added to the storage tank, or one of the cord bloods in the tank is removed, causing sudden temperature fluctuations in the tank. Such repeated temperature fluctuations eventually lead to stem cell death and reduced viability. Research has shown that transient warming events will reduce stem cell numbers. Millions of stem cells are lost due to transient warming. Another report shows that vapor nitrogen combined with transient warming events can cause a 20% loss of viability. As a result, the researchers warn cord blood banks to take precautions against transient warming events. This is because one of the most important factors in the success of a blood transfusion (transplantation) is the number of viable cells in the stored blood.